HyPerforma G3Lab, G3Lite, and G3Pro Controllers

Consistent bioprocess control designed for scalability

Thermo Scientific HyPerforma GXCore, G3Lab, G3Lite, and G3Pro Controllers provide ease of data transferability and scalability throughout your process. This bioprocess controller series incorporates innovative features that enhance productivity, data quality, and reproducibility required to optimize any process. Integrating flexibility and an open-architecture design, this platform allows the use of third-party vessels, as well as the Thermo Scientific HyPerforma Single-Use Bioreactor (S.U.B.).

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Choose a step in the workflow below to identify the ideal Bioprocess Controller

GXCore and G3Lab Models

HyPerforma G3Lab Bioprocess Controller

GXCore Bioprocess Controller

The core solution to scalability

The Thermo Scientific HyPerforma GXCore Bioprocess Controller is an innovative, open-architecture, cost-effective controller offering a compact design—enabling users to easily scale-up and adapt to suit specific process and application goals. The GXCore Bioprocess Controller can control most bench-scale single-use bioreactors and fermentors up to 15 L, regardless of manufacturer. Utilizing a small footprint to allow for more work space on the bench, the GXCore Bioprocess Controller is complete with all functionalities required for most research and process development applications.

Key features:

  • Scalability: ≤15 L
  • Reduced footprint and stackable
  • Auxiliary connections to allow future expansion and/or additional capabilities
  • User defined LED indicators on the front for easy alarm detection and process separation
  • Open-architecture capabilities to integrate with vessels from other suppliers, such as the Eppendorf BioBLU Single-Use Vessels and Sartorius UniVessel Benchtop Bioreactors
  • Suitable for both beginner and experienced researchers
G3-Lab-Controller

G3Lab Bioprocess Controller

Easy process scale-up or scale-down

The Thermo Scientific HyPerforma G3Lab Controller can control most brands of single-use or autoclavable bioreactors and fermentors that are ≤ 50 L, including stirred-tank and rocking models. The enclosure contains state-of-the-art transmitters along with power supplies, pumps, input/output (I/O) modules, and the hardware required to connect to the control network, providing maximum control capability.

Key features:

  • Scalability: ≤ 50 L
  • Open-architecture capabilities to integrate with vessels from other suppliers, such as the Eppendorf BioBLU Single-Use Vessels and Sartorius UniVessel Benchtop Bioreactors
  • The ability to build and manage complex, multi-feed dosing strategies
  • Allows for third-party peripheral integration as needed

View the ordering table to select the bioprocess controller and associated products that best fit your needs. ?

G3Lite Model

HyPerforma G3Lite Bioprocess Controller

G3Lite Bioprocess Controller

Modularity for scale-up

The Thermo Scientific HyPerforma G3Lite Bioprocess Controller is an open-architecture control system that can be integrated with most bioreactors and fermentors - regardless of manufacturer. The system consists of a control tower that leverages intelligent transmitters, mass flow controllers (MFCs), pumps, and sensors. This controller is fully self-contained, mobile, and can be operated as stand-alone (for one vessel) or networked for multiple vessels. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.

Key features:

  • Scalability: volumes 50 L to 2,000 L
  • Modularity: predefined configurations available for 50, 100, 250, 500, 1,000 and 2,000 L bioreactors
  • Touchscreen interface for easy data entry and control
  • Stand-alone or networked (for multiple vessels) 
  • Redundant pH and DO sensors

For volumes ≤ 50 L

The G3Lab Bioprocess Controller, primarily used in drug discovery and R&D is often chosen in the process development phase.

For volumes ≤ 15 L  

The GXCore Bioprocess Controller is a cost-effective, compact option, also suitable in the process development phase.

G3Pro Model

HyPerforma G3Pro Bioprocess Controller

G3Pro Bioprocess Controller

Versatility for scale-up

The Thermo Scientific HyPerforma G3Pro Bioprocess Controller contains many of the G3Lite Bioprocess Controller capabilities as an open-architecture, universal controller used to control most bioreactors and fermentors. These controllers enable an additional layer of versatility, allowing mobility and flexibility in terms of providing options for any reconfiguration or application expansion. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.

Key features:

  • Scalability: volumes 50 L to 2,000 L
  • Open-architecture capabilities to integrate with vessels from other suppliers
  • Single or dual cart mount option for easy mobility and reduced footprint
  • Touchscreen NEMA interface for easy data entry and control
  • Probe configuration options – flexible to connect electrochemical, single-use, or both for pH and DO measurements
  • Redundant sensor control mechanism
  • Can be adapted for multi-product applications

A stand-alone controller system for one vessel

The G3Lite Bioprocess Controller, primarily used in process development and clinical phases, is also suitable for commercial manufacturing when there is a need to have a stand-alone, modular controller system for one piece of equipment.

View the ordering table to select the bioprocess controller and associated products that best fit your needs. ?

GXCore and G3Lab Models

HyPerforma G3Lab Bioprocess Controller

GXCore Bioprocess Controller

The core solution to scalability

The Thermo Scientific HyPerforma GXCore Bioprocess Controller is an innovative, open-architecture, cost-effective controller offering a compact design—enabling users to easily scale-up and adapt to suit specific process and application goals. The GXCore Bioprocess Controller can control most bench-scale single-use bioreactors and fermentors up to 15 L, regardless of manufacturer. Utilizing a small footprint to allow for more work space on the bench, the GXCore Bioprocess Controller is complete with all functionalities required for most research and process development applications.

Key features:

  • Scalability: ≤15 L
  • Reduced footprint and stackable
  • Auxiliary connections to allow future expansion and/or additional capabilities
  • User defined LED indicators on the front for easy alarm detection and process separation
  • Open-architecture capabilities to integrate with vessels from other suppliers, such as the Eppendorf BioBLU Single-Use Vessels and Sartorius UniVessel Benchtop Bioreactors
  • Suitable for both beginner and experienced researchers
G3-Lab-Controller

G3Lab Bioprocess Controller

Easy process scale-up or scale-down

The Thermo Scientific HyPerforma G3Lab Controller can control most brands of single-use or autoclavable bioreactors and fermentors that are ≤ 50 L, including stirred-tank and rocking models. The enclosure contains state-of-the-art transmitters along with power supplies, pumps, input/output (I/O) modules, and the hardware required to connect to the control network, providing maximum control capability.

Key features:

  • Scalability: ≤ 50 L
  • Open-architecture capabilities to integrate with vessels from other suppliers, such as the Eppendorf BioBLU Single-Use Vessels and Sartorius UniVessel Benchtop Bioreactors
  • The ability to build and manage complex, multi-feed dosing strategies
  • Allows for third-party peripheral integration as needed

View the ordering table to select the bioprocess controller and associated products that best fit your needs. ?

G3Lite Model

HyPerforma G3Lite Bioprocess Controller

G3Lite Bioprocess Controller

Modularity for scale-up

The Thermo Scientific HyPerforma G3Lite Bioprocess Controller is an open-architecture control system that can be integrated with most bioreactors and fermentors - regardless of manufacturer. The system consists of a control tower that leverages intelligent transmitters, mass flow controllers (MFCs), pumps, and sensors. This controller is fully self-contained, mobile, and can be operated as stand-alone (for one vessel) or networked for multiple vessels. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.

Key features:

  • Scalability: volumes 50 L to 2,000 L
  • Modularity: predefined configurations available for 50, 100, 250, 500, 1,000 and 2,000 L bioreactors
  • Touchscreen interface for easy data entry and control
  • Stand-alone or networked (for multiple vessels) 
  • Redundant pH and DO sensors

For volumes ≤ 50 L

The G3Lab Bioprocess Controller, primarily used in drug discovery and R&D is often chosen in the process development phase.

For volumes ≤ 15 L  

The GXCore Bioprocess Controller is a cost-effective, compact option, also suitable in the process development phase.

G3Pro Model

HyPerforma G3Pro Bioprocess Controller

G3Pro Bioprocess Controller

Versatility for scale-up

The Thermo Scientific HyPerforma G3Pro Bioprocess Controller contains many of the G3Lite Bioprocess Controller capabilities as an open-architecture, universal controller used to control most bioreactors and fermentors. These controllers enable an additional layer of versatility, allowing mobility and flexibility in terms of providing options for any reconfiguration or application expansion. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.

Key features:

  • Scalability: volumes 50 L to 2,000 L
  • Open-architecture capabilities to integrate with vessels from other suppliers
  • Single or dual cart mount option for easy mobility and reduced footprint
  • Touchscreen NEMA interface for easy data entry and control
  • Probe configuration options – flexible to connect electrochemical, single-use, or both for pH and DO measurements
  • Redundant sensor control mechanism
  • Can be adapted for multi-product applications

A stand-alone controller system for one vessel

The G3Lite Bioprocess Controller, primarily used in process development and clinical phases, is also suitable for commercial manufacturing when there is a need to have a stand-alone, modular controller system for one piece of equipment.

View the ordering table to select the bioprocess controller and associated products that best fit your needs. ?


Related products used across the workflow from R&D to manufacturing

TruBio Bioprocess Automation Software

The TruBio software, powered by the Emerson DeltaV Distributed Control platform, provides easy-to-configure process control - eliminating the need to learn automation control programming. Developed for use with all Thermo Scientific controllers, TruBio software is designed to support easy scaling, data integrity and technology transfer and allow the ability to build sophisticated process control strategies. It provides flexibility to incorporate a wide range of equipment and manage multiple data streams from several unit operations. TruBio software has been developed according to GAMP 5 methods, and conforms to regulatory requirements for use in cGMP-compliant processes.

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Ordering information

Select the GXCore Bioprocess Controller and the most commonly paired products from the list below. Please speak to your sales representative to determine which mass flow controllers (MFCs), bioreactors, and automation software platforms will fit your need.

GXCore Bioprocess Controller

MFCs

HyPerforma Glass Bioreactors

HyPerforma Rocker Bioreactors and BioProcess Controllers (BPCs)

50 L HyPerforma Single-Use Bioreactors

Select the G3Lab Bioprocess Controller and the most commonly paired products from the list below. Please speak to your sales representative to determine which MFCs, bioreactors, and automation software platforms will fit your need.

G3Lab Bioprocess Controllers and HyPerforma Glass and Single-Use Bioreactors

G3Lab Bioprocess Controllers and HyPerforma Rocker Bioreactors and BPCs

Select the G3Lite Bioprocess Controller and the most commonly paired products from the list below. Please speak to your sales representative to determine which MFCs, bioreactors, and automation software platforms will fit your need.

For volumes 50 – 250 L

For volumes 500 – 2,000 L

Please speak to your sales representative to determine the type of G3Pro Bioprocess Controller and its associated products (MFCs, bioprocess equipment, and automation software platforms) will fit your needs.

Bioprocessing resources

Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing: