Browse stem cell biology pathways
Stem cells are undifferentiated cells that can both differentiate into any cell type and can continue to divide indefinitely—otherwise known as self-renewal. There are two broad types of stem cells, embryonic stem cells and adult stem cells, and both are now useful for a wide range of research, engineering, and disease modeling capacities. A number of pathways fall under this area, including the BMP and FGF pathways.
Bone morphogenetic proteins (BMPs) are a large subclass of the transforming growth factor-beta (TGF-beta) superfamily.
One of the most well characterized modulators of angiogenesis is the heparin-binding fibroblast growth factor (FGF).
Hematopoietic stem cells are classified into long-term, short-term, and multipotent progenitors, based on the extent of their self-renewal abilities.
Pluripotent cells are capable of forming virtually all of the possible tissue types found in human beings.
NANOG is a transcription factor transcribed in pluripotent stem cells and is down-regulated upon cell differentiation.